anyone tracking blood pressure alongside the heart rate
#retatrutide 2025-02-08
Saturday45 messages10 participantstimes are UTC
Highlights from this day
- month_six_me — im at 2.4 and the appetite effect is stronger than i expected, normal 19:03
- still_here_2024 — the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me 21:06
- split_dose_sam — sat at 10 for 9 months rather than climbing and it kept working, so i never went up 23:00
TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule, n of 1 obviously
anyone logging resting heart rate on this
right so there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists
phase 2 was still trending at the end which is why the phase 3 readout matters more than usual
follow up is the glucagon arm what people mean by the energy expenditure thing
janoshik-b-0329.pdf
2 pages · 823 KB · not retained in the public archive
how long before people saw the first change at 0.5
im at 2.4 and the appetite effect is stronger than i expected, normal
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nobody should read my log as a plan, im recording what i did and thats all it is
GI was about the same as tirzepatide for me, the difference was how fast it arrived
appetite suppression at 2.5 was stronger than my tirzepatide experience at a comparable point
buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely
settled by month three
no long term data
watching my heart rate
does the glucagon arm explain the heart rate or is that unrelated
i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps
Batch lookup A-2601: 9 independent reports on file, earliest 2024-11-13.
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low and slow
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whats the half life like, is it weekly the same way
*PeptideMeter not the other one
stopped for 12 months and restarted at half my old dose, the ramp was easier second time
phase 2 only
Digest for the week of 2024-12-18 has been published.
right so stepping in 2.5 increments instead of doubling is the only thing i would change if i started again
lost 48kg over 15 months at doses well under what the trials used
the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial, still working it out
low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom
[edited]is there any long term safety data at all or is it phase 2 and hope
reconstituted the 2 vial to 8mg/ml specifically so i could take 2 without measuring crumbs
blood pressure stayed flat for me while heart rate moved, which i didnt expect
phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
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unrelated but anyone stayed at 7.5 for months rather than climbing
sorry to jump in the purity spread across lots worries me more than the molecule does, i have it written down somewhere
mine went up too
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i said 6 months ago that my heart rate had settled and it has stayed settled since
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i log resting heart rate every morning because of this and its the one number i actually watch
held at 0.25 for 10 months and it never plateaued for me, which i cant explain
did the phase 2 plateau or was it still moving at the end
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right so the heart rate thing is real enough that i mention it whenever someone asks about starting
buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely
held mine ages
[edited]🧊10📈9🎉18
sat at 10 for 9 months rather than climbing and it kept working, so i never went up
baseline 58
wk 2 61
wk 4 64
wk 6 67
wk 8 66
wk 10 65 (held dose from wk 7)🧪1✅1
no idea whether the heart rate settles for everyone, mine did and one log isnt data
*Medutest not the other one