#retatrutide 2025-02-22

Saturday13 messages4 participantstimes are UTC

Highlights from this day

VialBot — Testing queue: 5 submissions open, 102 awaiting dispatch. 22:16
pin29g — coming back to this the heart rate thing is real enough that i mention it whenever someone asks about starting 22:32
pin29g — VendorInvestigate came back 97.4 on one lot and 98.1 on the next from the same WXT, both fine 23:26

Testing queue: 5 submissions open, 102 awaiting dispatch.

📈11

update on the earlier thing the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me

coming back to this the heart rate thing is real enough that i mention it whenever someone asks about starting

baseline  58
wk 2      61
wk 4      64
wk 6      67
wk 8      66
wk 10     65   (held dose from wk 7)

the half life supports weekly dosing and thats what ive done from the start

research use only

triple agonist yeah

lost 18kg over 7 months at doses well under what the trials used

📈2

phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan, still working it out

did the phase 2 plateau or was it still moving at the end

came off at 15 weeks because my resting rate stayed elevated and i didnt like it

is the glucagon arm what people mean by the energy expenditure thing

there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists, your mileage will differ

VendorInvestigate came back 97.4 on one lot and 98.1 on the next from the same WXT, both fine