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#retatrutide 2025-03-26

Wednesday20 messages4 participantstimes are UTC
Highlights from this day
  • panel_before_after — the honest position is this has less human evidence behind it than anything else discussed here 08:09
  • swirl_not_shake — appetite suppression at 12 was stronger than my tirzepatide experience at a comparable point the heart rate thing is real enough that i mention it whenever someone… 10:29
  • panel_before_after — low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom 10:44
  • panel_before_after — does the glucagon arm explain the heart rate or is that unrelated lost 34kg over 13 months at doses well under what the trials used 10:45
  • panel_before_after — i log resting heart rate every morning because of this and its the one number i actually watch 11:29
PB

the honest position is this has less human evidence behind it than anything else discussed here

anyone stayed at 5 for months rather than climbing

triple agonist yeah

genuine question is the phase 2 dosing anywhere near what people here run

SN

there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists

logging rhr daily

SL

no idea whether the heart rate settles for everyone, mine did and one log isnt data

TA

GI was about the same as tirzepatide for me, the difference was how fast it arrived

SL

did the phase 2 result actually come in higher than the tirzepatide numbers

SN

appetite suppression at 12 was stronger than my tirzepatide experience at a comparable point
the heart rate thing is real enough that i mention it whenever someone asks about starting

PB

low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom

does the glucagon arm explain the heart rate or is that unrelated
lost 34kg over 13 months at doses well under what the trials used

PB

i log resting heart rate every morning because of this and its the one number i actually watch