vialroom

#retatrutide 2025-04-22

Tuesday11 messages4 participantstimes are UTC
Highlights from this day
  • mg_per_ml — research use only is on every vial and i treat it as exactly that, nobody here is prescribing, someone check my working 17:29
  • spreadsheet_stu — the heart rate thing is real enough that i mention it whenever someone asks about starting 17:40
  • mg_per_ml — stopped for 8 months and restarted at half my old dose, the ramp was easier second time 17:44
VV

is there any long term safety data at all or is it phase 2 and hope

MP

reconstituted the 20 vial to 10mg/ml specifically so i could take 15 without measuring crumbs

SB

did the phase 2 result actually come in higher than the tirzepatide numbers

MP

research use only is on every vial and i treat it as exactly that, nobody here is prescribing, someone check my working

MP

my resting rate went up 3 bpm in the first month and came back most of the way by month 1, ymmv

SS

the heart rate thing is real enough that i mention it whenever someone asks about starting

Cited study
Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial
New England Journal of Medicine · 2023
48 weeks, dose-ranging. A Phase 2 result is not a safety record.

genuine question anyone reconstituting 10 vials to 10 so the steps come out smaller

MP

stopped for 8 months and restarted at half my old dose, the ramp was easier second time

🔥12❤️18
MP

phase 2 was still trending at the end which is why the phase 3 readout matters more than usual