vialroom

#retatrutide 2025-05-08

Thursday23 messages5 participantstimes are UTC
Highlights from this day
  • orfor_watch — people insist on small steps because the side effects arrive faster than on the other two 09:20
  • orfor_watch — is the glucagon arm what people mean by the energy expenditure thing 09:25
  • dexa_or_bia — ok so whats the half life like, is it weekly the same way 09:30
  • vienna_vial — the half life supports weekly dosing and thats what ive done from the start stepping in 0.25 increments instead of doubling is the only thing i would change if i… 10:11
OW

reconstituted the 5 vial to 5mg/ml specifically so i could take 5 without measuring crumbs

buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely

OW

people insist on small steps because the side effects arrive faster than on the other two

👀3📉17

the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial

is the glucagon arm what people mean by the energy expenditure thing

📉13⚠️9🎉13
DO

research use only is on every vial and i treat it as exactly that, nobody here is prescribing

ok so whats the half life like, is it weekly the same way

👍5🔥2🤝17

is there any long term safety data at all or is it phase 2 and hope

VV

the half life supports weekly dosing and thats what ive done from the start
stepping in 0.25 increments instead of doubling is the only thing i would change if i started again

how slow is low and slow here, four weeks a step or longer

DO

triple agonist meaning GLP-1, GIP and glucagon, have i got that right

held mine ages

blood pressure stayed flat for me while heart rate moved, which i didnt expect

ok so i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps

VV

held at 0.5 for 16 months and it never plateaued for me, which i cant explain

VV

anyone reconstituting 20 vials to 8 so the steps come out smaller

logging rhr daily

VV

triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history

RS

TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule, still working it out