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#retatrutide 2025-05-31

Saturday21 messages6 participantstimes are UTC
Highlights from this day
  • reship_rita — lost 48kg over 22 months at doses well under what the trials used 18:11
  • reship_rita — the half life supports weekly dosing and thats what ive done from the start 18:38
  • endotoxin_ed — ok so phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan 18:43
  • endotoxin_ed — is the glucagon arm what people mean by the energy expenditure thing 19:06
RR

why does everyone insist on smaller steps here than on the other two

RR

lost 48kg over 22 months at doses well under what the trials used

💀42

whats a sensible starting point, im seeing everything from 0.5 to 2

phase 2 was still trending at the end which is why the phase 3 readout matters more than usual

low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom

AA

is there any long term safety data at all or is it phase 2 and hope

RR

the half life supports weekly dosing and thats what ive done from the start

2🧪6
EE

ok so phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan

EE

back after 13 months, has anything actually been published since

is the glucagon arm what people mean by the energy expenditure thing

📉13⚠️15

reconstituted the 5 vial to 10mg/ml specifically so i could take 12 without measuring crumbs

GI was about the same as tirzepatide for me, the difference was how fast it arrived

whats the half life like, is it weekly the same way

RR

my resting rate went up 6 bpm in the first month and came back most of the way by month 22

QH

there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists