whats the half life like, is it weekly the same way
#retatrutide 2025-06-27
Friday38 messages9 participantstimes are UTC
Highlights from this day
- hair_month_four — while im here im at 0.25 and the appetite effect is stronger than i expected, normal 17:52
- VialBot — On this day 3 years ago this channel logged 123 messages. 18:58
- VialBot — Archive lookup: coelution_cai first appears in this channel on 2025-01-01. 19:00
- coelution_cai — research use only is on every vial and i treat it as exactly that, nobody here is prescribing 19:25
- rae_labels — is there any long term safety data at all or is it phase 2 and hope 19:39
logging rhr daily
glucagon is the new bit
phase 2 only
while im here im at 0.25 and the appetite effect is stronger than i expected, normal
👀5
how do people square the research use only framing with logging their own use
no long term data
smaller steps here
there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists
watching my heart rate
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me, i think
nobody should read my log as a plan, im recording what i did and thats all it is
On this day 3 years ago this channel logged 123 messages.
Archive lookup: coelution_cai first appears in this channel on 2025-01-01.
i said 8 months ago that my heart rate had settled and it has stayed settled since
quick one no idea whether the heart rate settles for everyone, mine did and one log isnt data
the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial
cant feel it honestly
follow up i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind
low and slow
for the archive low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom
appetite suppression at 15 was stronger than my tirzepatide experience at a comparable point
the honest position is this has less human evidence behind it than anything else discussed here
[edited]stopped for 6 months and restarted at half my old dose, the ramp was easier second time, not advice obviously
sat at 1 for 7 months rather than climbing and it kept working, so i never went up
did anyone come off because of the heart rate
the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial
follow up GI was about the same as tirzepatide for me, the difference was how fast it arrived, for what its worth
research use only is on every vial and i treat it as exactly that, nobody here is prescribing
👀7
reconstituted the 20 vial to 2mg/ml specifically so i could take 12 without measuring crumbs
is there any long term safety data at all or is it phase 2 and hope
😂14📈2
how long before people saw the first change at 5
Recon calculator: 30mg in 0.5ml = 8mg/ml.
the half life supports weekly dosing and thats what ive done from the start
🧪2
did the phase 2 plateau or was it still moving at the end
does the glucagon arm explain the heart rate or is that unrelated
Reminder set. I will post here in 3 days.
slightly off topic but i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps, i have it written down somewhere
anyone tracking blood pressure alongside the heart rate