phase 2 only
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#retatrutide 2025-07-10
Thursday31 messages6 participantstimes are UTC
Highlights from this day
- tokyo_taper — the purity spread across lots worries me more than the molecule does 20:01
- careful_claims — reconstituted the 10 vial to 5mg/ml specifically so i could take 5 without measuring crumbs came off at 15 weeks because my resting rate stayed elevated and i didnt… 20:28
- provincial_pat — anyone compared their VendorInvestigate purity across two different MKM lots 21:05
- careful_claims — i said 3 months ago that my heart rate had settled and it has stayed settled since 21:35
there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists
how slow is low and slow here, four weeks a step or longer
the purity spread across lots worries me more than the molecule does
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whats the half life like, is it weekly the same way
the half life supports weekly dosing and thats what ive done from the start, thats just me
quick one is the glucagon arm what people mean by the energy expenditure thing
low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom, your mileage will differ
held mine ages
reconstituted the 10 vial to 5mg/ml specifically so i could take 5 without measuring crumbs
came off at 15 weeks because my resting rate stayed elevated and i didnt like it
i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps
my resting heart rate is up about 4 bpm, did that settle for anyone
unrelated but i log resting heart rate every morning because of this and its the one number i actually watch
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sorry to jump in the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me, from memory
smaller steps here
research use only
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does the glucagon arm explain the heart rate or is that unrelated
anyone compared their VendorInvestigate purity across two different MKM lots
mine went up too
lot-log.csv
792 rows · not retained in the public archive
buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely
back after 11 months, has anything actually been published since
sat at 7.5 for 8 months rather than climbing and it kept working, so i never went up
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no long term data
logging rhr daily
TRIUMPH is phase 3
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i said 3 months ago that my heart rate had settled and it has stayed settled since
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cant feel it honestly
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held at 0.5 for 5 months and it never plateaued for me, which i cant explain, i have it written down somewhere
genuine question anyone stayed at 5 for months rather than climbing
the honest position is this has less human evidence behind it than anything else discussed here, thats one data point
glucagon is the new bit