#retatrutide 2025-07-30

Wednesday11 messages2 participantstimes are UTC

Highlights from this day

blind_submit — why does everyone insist on smaller steps here than on the other two 18:27
quiet_head_qi — is TRIUMPH the phase 3 programme blood pressure stayed flat for me while heart rate moved, which i didnt expect 18:29
blind_submit — sorry to jump in i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps, still working it out 20:08
quiet_head_qi — triple agonist meaning GLP-1, GIP and glucagon, have i got that right 20:54

cant feel it honestly

stopped for 11 months and restarted at half my old dose, the ramp was easier second time

the heart rate thing is real enough that i mention it whenever someone asks about starting

why does everyone insist on smaller steps here than on the other two

📈12🎉12🙏1

is TRIUMPH the phase 3 programme
blood pressure stayed flat for me while heart rate moved, which i didnt expect

baseline  58
wk 2      61
wk 4      64
wk 6      67
wk 8      66
wk 10     65   (held dose from wk 7)

buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely, i think

the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial

blood pressure stayed flat for me while heart rate moved, which i didnt expect

sorry to jump in i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps, still working it out

i log resting heart rate every morning because of this and its the one number i actually watch

triple agonist meaning GLP-1, GIP and glucagon, have i got that right

baseline  58
wk 2      61
wk 4      64
wk 6      67
wk 8      66
wk 10     65   (held dose from wk 7)