no idea whether the heart rate settles for everyone, mine did and one log isnt data
#retatrutide 2025-08-08
Friday28 messages6 participantstimes are UTC
Highlights from this day
- blank_run — my resting heart rate is up about 6 bpm, did that settle for anyone 20:07
- chain_of_custody — follow up people insist on small steps because the side effects arrive faster than on the other two 20:19
- VialBot — New independent result logged — WXT, lot A-2601, purity 98.1% (PeptideMeter). 20:57
- chain_of_custody — buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely 21:37
follow up the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
phase 2 was still trending at the end which is why the phase 3 readout matters more than usual, thats just me
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watching my heart rate
the heart rate thing is real enough that i mention it whenever someone asks about starting
i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps
did the phase 2 result actually come in higher than the tirzepatide numbers
my resting heart rate is up about 6 bpm, did that settle for anyone
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PeptideMeter came back 99.2 on one lot and 98.6 on the next from the same QST, both fine
follow up people insist on small steps because the side effects arrive faster than on the other two
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nobody should read my log as a plan, im recording what i did and thats all it is
lost 11kg over 4 months at doses well under what the trials used
anyone stayed at 0.5 for months rather than climbing
whats a sensible starting point, im seeing everything from 0.5 to 2
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Verification log updated: GL Biochem — evidence added, status unchanged.
New independent result logged — WXT, lot A-2601, purity 98.1% (PeptideMeter).
is TRIUMPH the phase 3 programme
no long term data
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did anyone come off because of the heart rate
sat at 12 for 6 months rather than climbing and it kept working, so i never went up
phase 2 only
[edited]baseline 58
wk 2 61
wk 4 64
wk 6 67
wk 8 66
wk 10 65 (held dose from wk 7)buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely
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mine went up too
is there any long term safety data at all or is it phase 2 and hope
low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom
anyone tracking blood pressure alongside the heart rate
smaller steps here
triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history
did the phase 2 plateau or was it still moving at the end