#retatrutide 2025-08-21

Thursday24 messages7 participantstimes are UTC

Highlights from this day

amsterdam_aliquot — i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps 18:33
ferritin_fay — the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial 18:37
amsterdam_aliquot — blood pressure stayed flat for me while heart rate moved, which i didnt expect 19:45

fibre_first 18:10

TRIUMPH is phase 3

fibre_first 18:25

logging rhr daily

escalation_anxiety 18:26

whats the half life like, is it weekly the same way

cold_start_cy 18:29

there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists

phase 2 was still trending at the end which is why the phase 3 readout matters more than usual, someone check my working
came off at 13 weeks because my resting rate stayed elevated and i didnt like it

amsterdam_aliquot 18:33

i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps

🤝1👀15⚠️10

snac_and_water 18:35

came off at 21 weeks because my resting rate stayed elevated and i didnt like it

ferritin_fay 18:37

the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial

📉9❤️13

escalation_anxiety 18:41

did the phase 2 plateau or was it still moving at the end

escalation_anxiety 19:02

the half life supports weekly dosing and thats what ive done from the start