people insist on small steps because the side effects arrive faster than on the other two
#retatrutide 2025-09-15
Monday27 messages6 participantstimes are UTC
Highlights from this day
- juno_joins — reconstituted the 10 vial to 5mg/ml specifically so i could take 1.7 without measuring crumbs, ill dig out the number 00:17
- VialBot — New independent result logged — GGPeps, lot B-0114, purity 96.8% (Janoshik). 01:34
- step_one_sian — came off at 20 weeks because my resting rate stayed elevated and i didnt like it, not advice obviously 02:19
- step_one_sian — there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists 03:09
reconstituted the 10 vial to 5mg/ml specifically so i could take 1.7 without measuring crumbs, ill dig out the number
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sat at 0.25 for 2 months rather than climbing and it kept working, so i never went up, thats just me
logging rhr daily
appetite suppression at 0.25 was stronger than my tirzepatide experience at a comparable point
triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history, thats one data point
anyone stayed at 7.5 for months rather than climbing
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watching my heart rate
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triple agonist meaning GLP-1, GIP and glucagon, have i got that right
the honest position is this has less human evidence behind it than anything else discussed here
did anyone come off because of the heart rate
New independent result logged — GGPeps, lot B-0114, purity 96.8% (Janoshik).
coming back to this how slow is low and slow here, four weeks a step or longer
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule, thats one data point
came off at 20 weeks because my resting rate stayed elevated and i didnt like it, not advice obviously
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low and slow
there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists
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research use only
TRIUMPH is phase 3
mine went up too
Janoshik came back 99 on one lot and 97.4 on the next from the same ERP, both fine
why does everyone insist on smaller steps here than on the other two
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whats a sensible starting point, im seeing everything from 0.5 to 2
no long term data
coming back to this anyone gone above 1 and what changed
triple agonist yeah