the purity spread across lots worries me more than the molecule does
#retatrutide 2025-09-19
Friday13 messages4 participantstimes are UTC
Highlights from this day
- oli_orals — research use only is on every vial and i treat it as exactly that, nobody here is prescribing 19:35
- oli_orals — whats a sensible starting point, im seeing everything from 0.5 to 2 19:36
- oli_orals — the honest position is this has less human evidence behind it than anything else discussed here 19:56
there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists
research use only is on every vial and i treat it as exactly that, nobody here is prescribing
⚠️1🔥1🙏8
whats a sensible starting point, im seeing everything from 0.5 to 2
🎉8
blood pressure stayed flat for me while heart rate moved, which i didnt expect
did the phase 2 result actually come in higher than the tirzepatide numbers
⚠️1
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me, ask me again in a month
triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history, from memory
the honest position is this has less human evidence behind it than anything else discussed here
💀1✅3
no idea whether the heart rate settles for everyone, mine did and one log isnt data
buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely
no long term data
💀1
follow up sat at 1 for 9 months rather than climbing and it kept working, so i never went up