vialroom

#retatrutide 2025-10-02

Thursday43 messages10 participantstimes are UTC
Highlights from this day
  • mira_pins — energy expenditure isnt something i could feel, though my sleep tracker disagreed with me 13:50
  • mira_pins — low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom 14:17
  • mira_pins — anyone reconstituting 2 vials to 2.5 so the steps come out smaller 14:54
  • reta_resting_hr — Medutest came back 98.6 on one lot and 97.4 on the next from the same SWB, both fine 16:13

did the phase 2 result actually come in higher than the tirzepatide numbers

TE

nobody should read my log as a plan, im recording what i did and thats all it is, someone check my working

does the glucagon arm explain the heart rate or is that unrelated

AA

GI was about the same as tirzepatide for me, the difference was how fast it arrived

LN

quick one is there any long term safety data at all or is it phase 2 and hope

VV

the honest position is this has less human evidence behind it than anything else discussed here, n of 1 obviously

AA

the purity spread across lots worries me more than the molecule does

VV

quick one whats the half life like, is it weekly the same way

im at 5 and the appetite effect is stronger than i expected, normal

VV

smaller steps here

transit-times.csv
821 rows · not retained in the public archive
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anyone gone above 0.25 and what changed

PP

sorry to jump in held at 12 for 19 months and it never plateaued for me, which i cant explain

TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule

SS

came off at 29 weeks because my resting rate stayed elevated and i didnt like it

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PP

lost 17kg over 5 months at doses well under what the trials used, ill dig out the number

whats a sensible starting point, im seeing everything from 0.5 to 2

MP

energy expenditure isnt something i could feel, though my sleep tracker disagreed with me

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MP

my resting rate went up 2 bpm in the first month and came back most of the way by month 18, i think

CC

i log resting heart rate every morning because of this and its the one number i actually watch

MP

low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom

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MP

anyone reconstituting 2 vials to 2.5 so the steps come out smaller

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i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps

ok so appetite suppression at 0.25 was stronger than my tirzepatide experience at a comparable point

i said 6 months ago that my heart rate had settled and it has stayed settled since

CC

buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely

my resting heart rate is up about 7 bpm, did that settle for anyone

phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan

reconstituted the 2 vial to 10mg/ml specifically so i could take 0.25 without measuring crumbs

MP

stepping in 15 increments instead of doubling is the only thing i would change if i started again

RR

Medutest came back 98.6 on one lot and 97.4 on the next from the same SWB, both fine