i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps
#retatrutide 2025-10-15
Wednesday41 messages8 participantstimes are UTC
Highlights from this day
- baseline_drift — no idea whether the heart rate settles for everyone, mine did and one log isnt data 16:44
- surpass_two — there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists 18:33
- combo_cai — anyone tracking blood pressure alongside the heart rate 18:37
- VialBot — New independent result logged — QSC, lot SG-1177, purity 96.8% (VendorInvestigate). 18:41
triple agonist meaning GLP-1, GIP and glucagon, have i got that right
unrelated but the half life supports weekly dosing and thats what ive done from the start
lost 48kg over 2 months at doses well under what the trials used
low and slow
[edited]stopped for 18 months and restarted at half my old dose, the ramp was easier second time
does the glucagon arm explain the heart rate or is that unrelated
is the glucagon arm what people mean by the energy expenditure thing
did anyone come off because of the heart rate
⚠️5
*PeptideMeter not the other one
glucagon is the new bit
follow up back after 7 months, has anything actually been published since
held mine ages
no idea whether the heart rate settles for everyone, mine did and one log isnt data
⚠️8🔥1
did the phase 2 plateau or was it still moving at the end
whats the half life like, is it weekly the same way
TRIUMPH is phase 3
anyone gone above 12 and what changed
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phase 2 only
i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind
the purity spread across lots worries me more than the molecule does
is the GI worse than tirzepatide or about the same
anyone reconstituting 30 vials to 2 so the steps come out smaller
anyone logging resting heart rate on this
energy expenditure isnt something i could feel, though my sleep tracker disagreed with me
logging rhr daily
[edited]coming back to this PeptideMeter came back 96.8 on one lot and 98.6 on the next from the same BCH, both fine
*Medutest not the other one
cant feel it honestly
there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists
baseline 58
wk 2 61
wk 4 64
wk 6 67
wk 8 66
wk 10 65 (held dose from wk 7)no long term data
anyone tracking blood pressure alongside the heart rate
💀9
triple agonist yeah
watching my heart rate
New independent result logged — QSC, lot SG-1177, purity 96.8% (VendorInvestigate).
i said 3 months ago that my heart rate had settled and it has stayed settled since
the heart rate thing is real enough that i mention it whenever someone asks about starting, i have it written down somewhere
research use only
how do people square the research use only framing with logging their own use
why does everyone insist on smaller steps here than on the other two
held at 15 for 10 months and it never plateaued for me, which i cant explain