vialroom

#retatrutide 2026-01-03

Saturday14 messages5 participantstimes are UTC
Highlights from this day
  • site_itch — quick one research use only is on every vial and i treat it as exactly that, nobody here is prescribing 17:40
  • site_itch — i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind, i could be wrong 17:41
  • mira_pins — energy expenditure isnt something i could feel, though my sleep tracker disagreed with me 18:13
  • group_buy_gwen — lost 45kg over 16 months at doses well under what the trials used, anyway 18:15
  • group_buy_gwen — the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me 18:18

low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom

quick one research use only is on every vial and i treat it as exactly that, nobody here is prescribing

😂1

i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind, i could be wrong

GB

nobody should read my log as a plan, im recording what i did and thats all it is

MP

why does everyone insist on smaller steps here than on the other two

settled by month three

energy expenditure isnt something i could feel, though my sleep tracker disagreed with me

baseline  58
wk 2      61
wk 4      64
wk 6      67
wk 8      66
wk 10     65   (held dose from wk 7)
GB

lost 45kg over 16 months at doses well under what the trials used, anyway

Cited study
Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial
New England Journal of Medicine · 2023
48 weeks, dose-ranging. A Phase 2 result is not a safety record.
💀4🙏11

the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me

MM

i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps