triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history
#retatrutide 2026-03-04
Wednesday16 messages5 participantstimes are UTC
Highlights from this day
- evidence_or_not — how long before people saw the first change at 2.5 01:00
- evidence_or_not — stepping in 2 increments instead of doubling is the only thing i would change if i started again 01:14
- swab_dry_first — the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial 01:15
- rory_reships — Janoshik came back 96.8 on one lot and 99.2 on the next from the same QST, both fine, ill dig out the number 03:16
- dez_domains — right so low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom, still working it out 03:25
how long before people saw the first change at 2.5
👍5
anyone gone above 5 and what changed
stepping in 2 increments instead of doubling is the only thing i would change if i started again
🤝10👀6
the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial
the heart rate thing is real enough that i mention it whenever someone asks about starting
mine went up too
how slow is low and slow here, four weeks a step or longer
is TRIUMPH the phase 3 programme
smaller steps here
why does everyone insist on smaller steps here than on the other two
triple agonist meaning GLP-1, GIP and glucagon, have i got that right
Janoshik came back 96.8 on one lot and 99.2 on the next from the same QST, both fine, ill dig out the number
does the energy expenditure claim show up as anything you can feel
right so low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom, still working it out
*Janoshik not the other one