nobody should read my log as a plan, im recording what i did and thats all it is
#retatrutide 2026-03-13
Friday31 messages8 participantstimes are UTC
Highlights from this day
- amsterdam_aliquot — appetite suppression at 2 was stronger than my tirzepatide experience at a comparable point 21:53
- amsterdam_aliquot — unrelated but the honest position is this has less human evidence behind it than anything else discussed here 22:05
- amsterdam_aliquot — does the glucagon arm explain the heart rate or is that unrelated 22:55
- assay_not_purity — low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom 23:05
phase 2 was still trending at the end which is why the phase 3 readout matters more than usual
anyone gone above 7.5 and what changed
mine went up too
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appetite suppression at 2 was stronger than my tirzepatide experience at a comparable point
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right so the heart rate thing is real enough that i mention it whenever someone asks about starting
cant feel it honestly
glucagon is the new bit
anyone stayed at 2 for months rather than climbing
unrelated but the honest position is this has less human evidence behind it than anything else discussed here
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the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
whats the half life like, is it weekly the same way
the purity spread across lots worries me more than the molecule does
i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind
phase 2 only
no idea whether the heart rate settles for everyone, mine did and one log isnt data
no long term data
GI was about the same as tirzepatide for me, the difference was how fast it arrived
sat at 2 for 9 months rather than climbing and it kept working, so i never went up, happy to be corrected
did the phase 2 plateau or was it still moving at the end
logging rhr daily
im at 5 and the appetite effect is stronger than i expected, normal
does the glucagon arm explain the heart rate or is that unrelated
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On this day 7 years ago this channel logged 28 messages.
low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom
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i said 9 months ago that my heart rate had settled and it has stayed settled since
the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial
TRIUMPH is phase 3
the half life supports weekly dosing and thats what ive done from the start
TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule