#retatrutide 2026-03-21

Saturday15 messages5 participantstimes are UTC

Highlights from this day

retention_time — unrelated but sat at 1 for 8 months rather than climbing and it kept working, so i never went up 07:25
septum_sal — phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan 07:30
LC_MS_Lena — for the archive lost 28kg over 23 months at doses well under what the trials used 10:35
LC_MS_Lena — update on the earlier thing GI was about the same as tirzepatide for me, the difference was how fast it arrived 11:26

i log resting heart rate every morning because of this and its the one number i actually watch

[edited]

TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule

appetite suppression at 0.25 was stronger than my tirzepatide experience at a comparable point

whats a sensible starting point, im seeing everything from 0.5 to 2

the purity spread across lots worries me more than the molecule does

unrelated but sat at 1 for 8 months rather than climbing and it kept working, so i never went up

baseline  58
wk 2      61
wk 4      64
wk 6      67
wk 8      66
wk 10     65   (held dose from wk 7)

im at 0.25 and the appetite effect is stronger than i expected, normal

phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan

😂16

logging rhr daily

right so reconstituted the 15 vial to 2.5mg/ml specifically so i could take 2.4 without measuring crumbs, thats one data point

how long before people saw the first change at 2.5

for the archive lost 28kg over 23 months at doses well under what the trials used

📈10

update on the earlier thing GI was about the same as tirzepatide for me, the difference was how fast it arrived

⚠️1✅1

the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial

the half life supports weekly dosing and thats what ive done from the start, n of 1 obviously