Purity check: no report on file for lot A-2601. Nothing logged either way.
#retatrutide 2026-03-26
Thursday53 messages12 participantstimes are UTC
Highlights from this day
- ghk_gia — is the phase 2 dosing anywhere near what people here run 14:41
- truncation_tru — anyone reconstituting 5 vials to 2 so the steps come out smaller 15:29
- sunday_shot — anyone gone above 2.5 and what changed 16:24
- ghk_gia — anyone compared their Medutest purity across two different SGN lots 18:25
phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan
smaller steps here
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slightly off topic but back after 5 months, has anything actually been published since
my resting heart rate is up about 8 bpm, did that settle for anyone
the honest position is this has less human evidence behind it than anything else discussed here
research use only
while im here triple agonist meaning GLP-1, GIP and glucagon, have i got that right
[edited]held at 2.4 for 1 months and it never plateaued for me, which i cant explain
the heart rate thing is real enough that i mention it whenever someone asks about starting
TRIUMPH is phase 3
why does everyone insist on smaller steps here than on the other two
sat at 1 for 6 months rather than climbing and it kept working, so i never went up
is the phase 2 dosing anywhere near what people here run
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how long before people saw the first change at 0.25
came off at 5 weeks because my resting rate stayed elevated and i didnt like it
logging rhr daily
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my resting rate went up 6 bpm in the first month and came back most of the way by month 24
blood pressure stayed flat for me while heart rate moved, which i didnt expect
no long term data
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anyone logging resting heart rate on this
anyone reconstituting 5 vials to 2 so the steps come out smaller
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the half life supports weekly dosing and thats what ive done from the start, i could be wrong
anyone stayed at 15 for months rather than climbing
GI was about the same as tirzepatide for me, the difference was how fast it arrived
slightly off topic but buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely, anyway
the heart rate thing is real enough that i mention it whenever someone asks about starting
the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial
Janoshik came back 99.4 on one lot and 98.6 on the next from the same CPC, both fine
i log resting heart rate every morning because of this and its the one number i actually watch
low and slow
the purity spread across lots worries me more than the molecule does
quick one anyone tracking blood pressure alongside the heart rate
did anyone come off because of the heart rate
[edited]does the energy expenditure claim show up as anything you can feel
stepping in 2.5 increments instead of doubling is the only thing i would change if i started again, your mileage will differ
held at 12 for 15 months and it never plateaued for me, which i cant explain
cant feel it honestly
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anyone gone above 2.5 and what changed
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does the glucagon arm explain the heart rate or is that unrelated
unrelated but how do people square the research use only framing with logging their own use
came off at 29 weeks because my resting rate stayed elevated and i didnt like it
unrelated but lost 42kg over 25 months at doses well under what the trials used
did the phase 2 result actually come in higher than the tirzepatide numbers
whats a sensible starting point, im seeing everything from 0.5 to 2
is TRIUMPH the phase 3 programme
whats the half life like, is it weekly the same way
glucagon is the new bit
phase 2 only
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triple agonist yeah
appetite suppression at 7.5 was stronger than my tirzepatide experience at a comparable point
anyone compared their Medutest purity across two different SGN lots
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phase 2 was still trending at the end which is why the phase 3 readout matters more than usual
im at 5 and the appetite effect is stronger than i expected, normal
the purity spread across lots worries me more than the molecule does
is the glucagon arm what people mean by the energy expenditure thing
triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history
phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan