vialroom

#retatrutide 2026-06-27

Saturday45 messages12 participantstimes are UTC
Highlights from this day
  • freeze_thaw — did anyone come off because of the heart rate 07:13
  • freeze_thaw — whats a sensible starting point, im seeing everything from 0.5 to 2 07:38
  • food_noise_off — there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists 08:14
FT

TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule

FI

energy expenditure isnt something i could feel, though my sleep tracker disagreed with me

did anyone come off because of the heart rate

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FT

whats a sensible starting point, im seeing everything from 0.5 to 2

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FN

no idea whether the heart rate settles for everyone, mine did and one log isnt data

[edited]
FN

sorry to jump in how slow is low and slow here, four weeks a step or longer

there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists

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SI

Medutest came back 98.6 on one lot and 99 on the next from the same SSA, both fine
i log resting heart rate every morning because of this and its the one number i actually watch

SI

anyone compared their Janoshik purity across two different GGPeps lots

SI

i said 7 months ago that my heart rate had settled and it has stayed settled since

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RT

reconstituted the 20 vial to 4mg/ml specifically so i could take 0.5 without measuring crumbs, ill dig out the number

whats the half life like, is it weekly the same way

FF

phase 2 was still trending at the end which is why the phase 3 readout matters more than usual

FF

anyone reconstituting 10 vials to 2 so the steps come out smaller

FF

triple agonist meaning GLP-1, GIP and glucagon, have i got that right

RT

did the phase 2 result actually come in higher than the tirzepatide numbers

VB

Batch lookup G-0641: 5 independent reports on file, earliest 2026-01-28.

people insist on small steps because the side effects arrive faster than on the other two

GI was about the same as tirzepatide for me, the difference was how fast it arrived

TN

the purity spread across lots worries me more than the molecule does

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IO

low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom

[edited]
IO

slightly off topic but anyone stayed at 2.4 for months rather than climbing

AA

how do people square the research use only framing with logging their own use

AA

why does everyone insist on smaller steps here than on the other two

AA

right so the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial

*Janoshik not the other one

phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan

[edited]
FF

i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind

my resting rate went up 4 bpm in the first month and came back most of the way by month 26

buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely, thats one data point

research use only

ST

back after 25 months, has anything actually been published since

smaller steps here

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BS

the half life supports weekly dosing and thats what ive done from the start

SI

held at 7.5 for 5 months and it never plateaued for me, which i cant explain