i keep a written note of every dose

nobody in here can tell you what a safe dose is because nobody has that number, and saying so is the honest answer

not generalising from that

what we actually know i log resting heart rate every morning because of this and its the one number i actually watch, happy to be pointed at better data

evidence standards apply

stepping in 2.5 increments instead of doubling is the only thing i would change if i started again

interesting mechanistically

energy expenditure isnt something i could feel, though my sleep tracker disagreed with me

settled by month three

a baseline panel before starting is the only way to say anything at all about your own numbers afterwards, written down with the date

assays are worth having on anything in this channel because the reference material is scarcer, not medical advice, obviously

there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists, no idea if it generalises

from eight months of rhr data people here go in smaller steps because the evidence is thinner, and that is caution rather than pharmacology, that is extrapolation

i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind

strict channel so nobody here is your clinician and this channel is the last place that should be treated as one

phase 2 reading the honest answer is that the phase two data is what we have and it does not cover long term anything, happy to be pointed at better data