the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing
#semaglutide 2024-02-10
- retention_time — 4 months at 2.4 and the honest summary is diminishing returns after the first half, still working it out 11:32
- retention_time — i stayed on 1.7 for 20 months and never went to 2.4, appetite was already where i needed it, not advice obviously 11:35
- retention_time — anyone compared their 10 vial dosing against the pen increments 11:50
- retention_time — i dont think the plateau is a dose problem most of the time, but i cant prove that 11:58
4 months at 2.4 and the honest summary is diminishing returns after the first half, still working it out
[edited]the appetite effect faded for me around 22 months and going up fixed it for a while
i stayed on 1.7 for 20 months and never went to 2.4, appetite was already where i needed it, not advice obviously
going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure
lost about 43kg on the low doses before i even got to 1, which surprised me
the long half life flattens the trough more than people expect, i never felt a day seven dip
anyone compared their 10 vial dosing against the pen increments
i dont think the plateau is a dose problem most of the time, but i cant prove that