vialroom

#semaglutide 2024-07-08

Monday16 messages3 participantstimes are UTC
Highlights from this day
  • tare_weight — slightly off topic but went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down 17:00
  • surpass_two — the plateau hit me at 18 weeks and moved again about a month later without a dose change went to 2.4 and the extra suppression wasnt worth the GI for me, so i came… 17:06
  • surpass_two — genuine question vial units and pen clicks are different systems, mixing the two is how people end up wrong 17:18
TW

SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial

i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication

TW

slightly off topic but went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down

Cited study
Effects of Semaglutide on Chronic Kidney Disease in Type 2 Diabetes (FLOW)
New England Journal of Medicine · 2024
Renal outcomes. The one that changed a lot of nephrologists’ minds.

FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure

licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose

ST

the plateau hit me at 18 weeks and moved again about a month later without a dose change
went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down

dose day is sunday for me only because thats when i remember, not because sunday matters

vials not pens here

held at 7.5 and lost 96lb over 23 months, slower than the trials and fine by me

genuine question vial units and pen clicks are different systems, mixing the two is how people end up wrong

[edited]
👍8💀2

going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution

PF

my plateau was the scale stopping while appetite stayed suppressed, which is a different problem

i stayed on 1.7 for 11 months and never went to 2.4, appetite was already where i needed it