vialroom

#semaglutide 2024-07-14

Sunday36 messages9 participantstimes are UTC
Highlights from this day
  • VialBot — Reminder for tarpit_tam: dose day is today. Set 8 days ago. 17:56
  • two_four_ceiling — im 2 months in at 12 and the appetite effect faded, is that a thing 18:10
  • VialBot — Assay note: TFC lot C-4402 reported at 98.6% of label content. 19:09
  • third_shift — going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution 20:36
KF

moving my dose day by a day or two never did anything noticeable for me

update on the earlier thing back after 2 months off, do i restart at 0.25 or somewhere higher

TT

my 20 vial in 2.5ml gives 8mg/ml so 10 lands on 8 units, thats why i picked that volume

[edited]
TT

how long till steady state, ive read the half life is about a week

VB

Reminder for tarpit_tam: dose day is today. Set 8 days ago.

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TF

im 2 months in at 12 and the appetite effect faded, is that a thing

Cited study
Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP 1)
New England Journal of Medicine · 2021
68 weeks, semaglutide 2.4mg weekly against placebo, with lifestyle intervention in both arms.
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TF

unrelated but my plateau was the scale stopping while appetite stayed suppressed, which is a different problem

TF

vial units and pen clicks are different systems, mixing the two is how people end up wrong

TS

€94 a month for compounded against what brand costs locally is why most people here use vials, happy to be corrected

TS

is the plateau at 6 weeks normal or am i doing something wrong

LN

i stayed on 1.7 for 11 months and never went to 2.4, appetite was already where i needed it

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VB

Assay note: TFC lot C-4402 reported at 98.6% of label content.

BS

steady state is the bit people skip, judging a new dose after eight days tells you almost nothing

held there too

does the licensed ceiling for weight differ from the diabetes one

BS

licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose

PM

anyone compared their 4 vial dosing against the pen increments

VB

Batch lookup SG-1177: 2 independent reports on file, earliest 2024-01-01.

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KF

does anyone actually run a five week step instead of four

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held at 1.7 and lost 51lb over 9 months, slower than the trials and fine by me, n of 1 obviously

2.4 is the ceiling

half life is about a week so youre roughly four to five weeks to steady state on any new dose

went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step

BS

the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing

TS

going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution

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i dont think the plateau is a dose problem most of the time, but i cant prove that

LN

genuine question STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping

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