vialroom

#semaglutide 2024-10-21

Monday22 messages3 participantstimes are UTC
Highlights from this day
  • hard_stop_hal — how long till steady state, ive read the half life is about a week 20:43
  • u100_pat — vial units and pen clicks are different systems, mixing the two is how people end up wrong the plateau hit me at 24 weeks and moved again about a month later without… 20:51
  • hard_stop_hal — right so did anybody find a difference between SGN and pharmacy at the same 12 22:01

how long till steady state, ive read the half life is about a week

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right so licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose

U1

my dose day drifted from friday to sunday, does that reset anything

vial units and pen clicks are different systems, mixing the two is how people end up wrong
the plateau hit me at 24 weeks and moved again about a month later without a dose change

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HS

my plateau was the scale stopping while appetite stayed suppressed, which is a different problem, not advice obviously

FA

the long half life flattens the trough more than people expect, i never felt a day seven dip, anyway

coming back to this back after 14 months off, do i restart at 0.25 or somewhere higher

is the plateau at 27 weeks normal or am i doing something wrong

U1

unrelated but €55 a month for compounded against what brand costs locally is why most people here use vials

FA

STEP 1 ran to 68 weeks. thats the one everyone half remembers

[edited]
FA

brand vs compounded, is there a difference people can actually feel

fridge-temps.csv
339 rows · not retained in the public archive

whats the actual licensed ceiling, i keep seeing different numbers

held at 2.5 and lost 36lb over 2 months, slower than the trials and fine by me

FA

restarted after 6 months off at a low dose and the nausea arrived exactly like the first time

went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step

HS

half life is about a week so youre roughly four to five weeks to steady state on any new dose
changed my mind on the four week rule, i think it depends entirely on how the current dose feels

HS

right so did anybody find a difference between SGN and pharmacy at the same 12

Trial scheduleWhat most people here do
Step interval4 weeks, fixed4-12 weeks, on symptoms
Holdingprotocol deviationnormal and expected
Top dosereached by designoften never reached
Coming downnot studiedcommon at maintenance
HS

unrelated but was FLOW the one that ran to 68 weeks or am i mixing them up

FA

21 months at 2.4 and the honest summary is diminishing returns after the first half, someone check my working
the long half life flattens the trough more than people expect, i never felt a day seven dip