vialroom

#semaglutide 2024-10-25

Friday32 messages5 participantstimes are UTC
Highlights from this day
  • lot_number_lou — i held at 0.25 for 2 months and it was the best decision i made 18:54
  • lot_number_lou — while im here my plateau was the scale stopping while appetite stayed suppressed, which is a different problem 20:00
  • mag_citrate — STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping 20:53
LM

lost about 45kg on the low doses before i even got to 1, which surprised me

LN

£38 a month for compounded against what brand costs locally is why most people here use vials, someone check my working

Cited study
Semaglutide vs Liraglutide for Weight Loss in Adults with Overweight or Obesity (STEP 8)
JAMA · 2022
Weekly against daily, head to head.

half life is about a week so youre roughly four to five weeks to steady state on any new dose

restarted after 14 months off at a low dose and the nausea arrived exactly like the first time

i held at 0.25 for 2 months and it was the best decision i made

wk 1-4    0.25mg
wk 5-10   0.50mg   (held 2 extra weeks)
wk 11-14  1.00mg
wk 15-26  1.70mg   (held, long)
wk 27+    2.40mg

held there too

while im here my plateau was the scale stopping while appetite stayed suppressed, which is a different problem

❤️10⚠️11📉12

does the seven day half life mean the last two days are weaker

🙏1👀1🎉3

i dont think the plateau is a dose problem most of the time, but i cant prove that

LM

did anybody find a difference between SWB and pharmacy at the same 0.25

the long half life flattens the trough more than people expect, i never felt a day seven dip

brand vs compounded, is there a difference people can actually feel

LM

is the plateau at 29 weeks normal or am i doing something wrong
my plateau was the scale stopping while appetite stayed suppressed, which is a different problem

LM

vial units and pen clicks are different systems, mixing the two is how people end up wrong

my PeptideMeter report on the TFC vial came back 99.2 against a certificate saying 99

STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping

👍16😂8

*that should say weekly

was FLOW the one that ran to 68 weeks or am i mixing them up

MC

update on the earlier thing STEP is several trials, so saying STEP said x is usually wrong without a number after it, ask me again in a month

Cited study
Effect of Semaglutide Coadministered with Intensive Behavioural Therapy (STEP 3)
JAMA · 2021
Semaglutide plus intensive behavioural therapy and a low-calorie diet run-in.
MC

anyone gone from 0.25 straight to 0.5 or is that too big a jump