STEP is several trials, so saying STEP said x is usually wrong without a number after it
#semaglutide 2024-11-10
Sunday11 messages3 participantstimes are UTC
Highlights from this day
did anybody find a difference between WWB and pharmacy at the same 2.5
vials not pens here
how long till steady state, ive read the half life is about a week
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
did anyone hold at 1 longer than four weeks before going up
vial units and pen clicks are different systems, mixing the two is how people end up wrong
steady state is the bit people skip, judging a new dose after eight days tells you almost nothing, for what its worth
i dont think the plateau is a dose problem most of the time, but i cant prove that
2.4 is the ceiling
STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping
the long half life flattens the trough more than people expect, i never felt a day seven dip
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