went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down
#semaglutide 2024-11-12
Tuesday32 messages9 participantstimes are UTC
Highlights from this day
- identity_shift — i dont think the plateau is a dose problem most of the time, but i cant prove that 13:54
- surpass_two — changed my mind on the four week rule, i think it depends entirely on how the current dose feels 14:23
- cold_pack_carla — back after 11 months off, do i restart at 0.25 or somewhere higher 16:55
- charge_state — is the plateau usually appetite coming back or just the scale stopping 17:47
i dont think the plateau is a dose problem most of the time, but i cant prove that
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whats the actual licensed ceiling, i keep seeing different numbers
im 23 months in at 12 and the appetite effect faded, is that a thing
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i stayed on 1.7 for 7 months and never went to 2.4, appetite was already where i needed it
wk 1-4 0.25mg
wk 5-10 0.50mg (held 2 extra weeks)
wk 11-14 1.00mg
wk 15-26 1.70mg (held, long)
wk 27+ 2.40mgplateaus move
£72 a month for compounded against what brand costs locally is why most people here use vials
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does the licensed ceiling for weight differ from the diabetes one
thats STEP 1
how many weeks before you noticed anything at 7.5
changed my mind on the four week rule, i think it depends entirely on how the current dose feels
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SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
give it four weeks
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right so is there a reason to hold at 1.7 rather than going to 2.4
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
held there too
[edited]STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping, i could be wrong
steady state takes weeks
did the STEP 4 withdrawal arm show what i think it showed
2.4 is the ceiling
im at 15 and stuck, did anyone break a plateau without going up
while im here what did SELECT actually measure, i see it quoted for everything
back after 11 months off, do i restart at 0.25 or somewhere higher
wk 1-4 0.25mg
wk 5-10 0.50mg (held 2 extra weeks)
wk 11-14 1.00mg
wk 15-26 1.70mg (held, long)
wk 27+ 2.40mg😂6
how long did the first 41kg take for people at the low doses
my plateau was the scale stopping while appetite stayed suppressed, which is a different problem
compounded and brand felt the same to me at 12, which is one person and nothing more
steady state is the bit people skip, judging a new dose after eight days tells you almost nothing
quick one does the seven day half life mean the last two days are weaker
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New independent result logged — SWB, lot H-2814, purity 98.6% (VendorInvestigate).
Batch lookup A-2601: 6 independent reports on file, earliest 2024-02-20.
lost about 19kg on the low doses before i even got to 1, which surprised me
slower worked better
is the plateau usually appetite coming back or just the scale stopping
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