vialroom

#semaglutide 2025-01-13

Monday40 messages12 participantstimes are UTC
Highlights from this day
  • cold_pack_carla — going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution 21:55
  • night_pin — my PeptideMeter report on the ERP vial came back 98.6 against a certificate saying 98.1 22:30
  • VialBot — Reminder set. I will post here in 4 days. 22:44
  • secretagogue_sy — the plateau hit me at 23 weeks and moved again about a month later without a dose change 23:07
  • secretagogue_sy — my 10 vial in 0.5ml gives 2.5mg/ml so 2.5 lands on 10 units, thats why i picked that volume 23:10

went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step

⚠️2🔥7
AA

compounded and brand felt the same to me at 2, which is one person and nothing more

slower worked better

AA

update on the earlier thing is 2.4 the top or do people go past it

SD

half life is about a week so youre roughly four to five weeks to steady state on any new dose

for the archive changed my mind on the four week rule, i think it depends entirely on how the current dose feels

TM

licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose, not advice obviously

*that should say weekly

CP

going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution

🎉5❤️18🙏4

steady state is the bit people skip, judging a new dose after eight days tells you almost nothing

not the same trial

2.4 is the ceiling

NP

was SURMOUNT-1 the one that ran to 68 weeks or am i mixing them up

SN

went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down

STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping

NP

my PeptideMeter report on the ERP vial came back 98.6 against a certificate saying 98.1

📉17

if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule

vials not pens here

VB

Reminder set. I will post here in 4 days.

📉1👀9
NP

STEP is several trials, so saying STEP said x is usually wrong without a number after it

CC

22 months at 2.4 and the honest summary is diminishing returns after the first half
moving my dose day by a day or two never did anything noticeable for me

SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial

1
NP

update on the earlier thing does moving my dose day by two days matter with a seven day half life

😂3
CC

did anyone titrate slower than four weeks a step and how did that go

😂1🤝8
NP

STEP 1 ran to 68 weeks. thats the one everyone half remembers

[edited]
SS

the plateau hit me at 23 weeks and moved again about a month later without a dose change

🧪16

i dont think the plateau is a dose problem most of the time, but i cant prove that

my 10 vial in 0.5ml gives 2.5mg/ml so 2.5 lands on 10 units, thats why i picked that volume

👀2💀12
MM

vial units and pen clicks are different systems, mixing the two is how people end up wrong

🙏3📉1🔥2
MM

restarted after 3 months off at a low dose and the nausea arrived exactly like the first time

SS

i stayed on 1.7 for 4 months and never went to 2.4, appetite was already where i needed it

medutest-report-h-2814.pdf
3 pages · 910 KB · not retained in the public archive
VI

did anyone hold at 2 longer than four weeks before going up