vialroom

#semaglutide 2025-01-28

Tuesday12 messages5 participantstimes are UTC
Highlights from this day
  • tarpit_tam — licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose 21:36
  • two_four_ceiling — SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial 21:38
  • quiet.hours — restarted after 19 months off at a low dose and the nausea arrived exactly like the first time, n of 1 obviously 22:00
A1

moving my dose day by a day or two never did anything noticeable for me

TT

licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose

Cited study
Semaglutide vs Liraglutide for Weight Loss in Adults with Overweight or Obesity (STEP 8)
JAMA · 2022
Weekly against daily, head to head.
TF

SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial

2⚠️2🧊1

half life is about a week so youre roughly four to five weeks to steady state on any new dose

QH

restarted after 19 months off at a low dose and the nausea arrived exactly like the first time, n of 1 obviously

💀5
TF

if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule, i think

TF

$55 a month for compounded against what brand costs locally is why most people here use vials
my plateau was the scale stopping while appetite stayed suppressed, which is a different problem

20 months at 2.4 and the honest summary is diminishing returns after the first half, your mileage will differ

whats the actual licensed ceiling, i keep seeing different numbers