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#semaglutide 2025-04-09

Wednesday23 messages5 participantstimes are UTC
Highlights from this day
  • a1c_lag — moving my dose day by a day or two never did anything noticeable for me 10:00
  • back_from_away — im at 15 and stuck, did anyone break a plateau without going up 11:27
  • a1c_lag — slightly off topic but is 2.4 the top or do people go past it 11:36
  • back_from_away — the long half life flattens the trough more than people expect, i never felt a day seven dip, your mileage will differ 11:42
A1

went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down

*PeptideMeter not the other one

moving my dose day by a day or two never did anything noticeable for me

⚠️6
AA

dose day is sunday for me only because thats when i remember, not because sunday matters, someone check my working

AA

back after 16 months off, do i restart at 0.25 or somewhere higher

does anyone actually run a five week step instead of four

BF

im at 15 and stuck, did anyone break a plateau without going up

Cited study
Semaglutide vs Liraglutide for Weight Loss in Adults with Overweight or Obesity (STEP 8)
JAMA · 2022
Weekly against daily, head to head.
A1

slightly off topic but is 2.4 the top or do people go past it

💀9

i stayed on 1.7 for 21 months and never went to 2.4, appetite was already where i needed it, i think

slower worked better

BF

the long half life flattens the trough more than people expect, i never felt a day seven dip, your mileage will differ

steady state takes weeks

BF

follow up STEP is several trials, so saying STEP said x is usually wrong without a number after it

the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing

plateaus move

NP

is the plateau at 26 weeks normal or am i doing something wrong

TS

same dose day

weights-monthly.csv
651 rows · not retained in the public archive