the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing
#semaglutide 2025-05-11
Sunday15 messages4 participantstimes are UTC
Highlights from this day
- lot_number_lou — if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule 17:22
- VialBot — Testing queue: 2 submissions open, 93 awaiting dispatch. 17:24
- lot_number_lou — dose day is sunday for me only because thats when i remember, not because sunday matters, happy to be corrected 18:05
- relabel_watch — lost about 14kg on the low doses before i even got to 1, which surprised me the appetite effect faded for me around 18 months and going up fixed it for a while 21:04
if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule
🤝1👀13
*Medutest not the other one
Testing queue: 2 submissions open, 93 awaiting dispatch.
was SELECT the one that ran to 68 weeks or am i mixing them up
STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping
licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose
dose day is sunday for me only because thats when i remember, not because sunday matters, happy to be corrected
sorry to jump in my 30 vial in 2.5ml gives 8mg/ml so 12 lands on 8 units, thats why i picked that volume
not the same trial
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
does the licensed ceiling for weight differ from the diabetes one
the plateau hit me at 4 weeks and moved again about a month later without a dose change
sorry to jump in STEP is several trials, so saying STEP said x is usually wrong without a number after it
vial units and pen clicks are different systems, mixing the two is how people end up wrong
lost about 14kg on the low doses before i even got to 1, which surprised me
the appetite effect faded for me around 18 months and going up fixed it for a while