vialroom

#semaglutide 2025-06-14

Saturday34 messages7 participantstimes are UTC
Highlights from this day
  • two_three_lifts — five week steps worked better for me than four, purely on how the second week felt 20:16
  • protein_floor — restarted after 8 months off at a low dose and the nausea arrived exactly like the first time 20:28
  • igf_one_ivy — was SURMOUNT-OSA the one that ran to 68 weeks or am i mixing them up 22:09
PF

STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping

*that should say weekly

PS

steady state is the bit people skip, judging a new dose after eight days tells you almost nothing

3😂4📈2
TT

five week steps worked better for me than four, purely on how the second week felt

💀12📉3🧊2

whats the actual licensed ceiling, i keep seeing different numbers

IO

is the plateau at 9 weeks normal or am i doing something wrong

PF

restarted after 8 months off at a low dose and the nausea arrived exactly like the first time

💀1🤝3🧪11
IO

held at 10 and lost 80lb over 10 months, slower than the trials and fine by me

give it four weeks

what did SELECT actually measure, i see it quoted for everything

how many weeks before you noticed anything at 0.5

plateaus move

medutest-report-b-0114.pdf
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PF

i stayed on 1.7 for 18 months and never went to 2.4, appetite was already where i needed it

follow up changed my mind on the four week rule, i think it depends entirely on how the current dose feels, not advice obviously

PF

my Medutest report on the WWB vial came back 99 against a certificate saying 99.2

PP

if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule

PP

does the licensed ceiling for weight differ from the diabetes one

U1

how long till steady state, ive read the half life is about a week

U1

while im here the long half life flattens the trough more than people expect, i never felt a day seven dip

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sorry to jump in moving my dose day by a day or two never did anything noticeable for me

IO

compounded and brand felt the same to me at 2.4, which is one person and nothing more
if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule

CC

mine faded too

Trial scheduleWhat most people here do
Step interval4 weeks, fixed4-12 weeks, on symptoms
Holdingprotocol deviationnormal and expected
Top dosereached by designoften never reached
Coming downnot studiedcommon at maintenance

dose day is sunday for me only because thats when i remember, not because sunday matters, n of 1 obviously

same dose day

IO

£94 a month for compounded against what brand costs locally is why most people here use vials