update on the earlier thing the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing
#semaglutide 2025-08-02
Saturday38 messages8 participantstimes are UTC
Highlights from this day
- vik_verifies — is the plateau usually appetite coming back or just the scale stopping 01:59
- residual_solvent — follow up went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step going slow cost me nothing except time and saved me two bad… 02:15
- residual_solvent — did the STEP 4 withdrawal arm show what i think it showed 03:30
- mira_pins — did anybody find a difference between SSA and pharmacy at the same 12 04:11
- split_dose_sam — quick one anyone gone from 5 straight to 10 or is that too big a jump 10:19
is the plateau usually appetite coming back or just the scale stopping
wk 1-4 0.25mg
wk 5-10 0.50mg (held 2 extra weeks)
wk 11-14 1.00mg
wk 15-26 1.70mg (held, long)
wk 27+ 2.40mgfollow up went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step
going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
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seven days ish
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4 months at 2.4 and the honest summary is diminishing returns after the first half
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is the plateau at 18 weeks normal or am i doing something wrong
changed my mind on the four week rule, i think it depends entirely on how the current dose feels
did the STEP 4 withdrawal arm show what i think it showed
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SELECT wasnt weight
did anybody find a difference between SSA and pharmacy at the same 12
same dose day
update on the earlier thing vial units and pen clicks are different systems, mixing the two is how people end up wrong, not advice obviously
$38 a month for compounded against what brand costs locally is why most people here use vials
does the licensed ceiling for weight differ from the diabetes one
went too fast once
follow up is there a reason to hold at 1.7 rather than going to 2.4
STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping
does moving my dose day by two days matter with a seven day half life
SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial, anyway
what did SELECT actually measure, i see it quoted for everything
give it four weeks
thats STEP 1
moving my dose day by a day or two never did anything noticeable for me
dose day is sunday for me only because thats when i remember, not because sunday matters
vials not pens here
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steady state takes weeks
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while im here half life is about a week so youre roughly four to five weeks to steady state on any new dose
held there too
quick one anyone gone from 5 straight to 10 or is that too big a jump
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not the same trial
going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution, ill dig out the number
[edited]held at 2 and lost 66lb over 9 months, slower than the trials and fine by me
going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
*that should say weekly
my dose day drifted from friday to sunday, does that reset anything
mine faded too
brand vs compounded, is there a difference people can actually feel
five week steps worked better for me than four, purely on how the second week felt
back after 3 months off, do i restart at 0.25 or somewhere higher