held at 1.7 and lost 29lb over 4 months, slower than the trials and fine by me
#semaglutide 2025-08-27
Wednesday34 messages7 participantstimes are UTC
Highlights from this day
i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure
my plateau was the scale stopping while appetite stayed suppressed, which is a different problem
held there too
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STEP 1 ran to 68 weeks. thats the one everyone half remembers
SELECT wasnt weight
03:43marrow.mod pinned a message to this channel
unrelated but went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down, anyway
dose day is sunday for me only because thats when i remember, not because sunday matters
sorry to jump in the appetite effect faded for me around 25 months and going up fixed it for a while, for what its worth
i dont think the plateau is a dose problem most of the time, but i cant prove that
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
how did people handle the jump from 1 to 1.7
$72 a month for compounded against what brand costs locally is why most people here use vials
not the same trial
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
five week steps worked better for me than four, purely on how the second week felt
is 2.4 the top or do people go past it
Reminder for tablet_tam: dose day is today. Set 8 days ago.
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same dose day
thats STEP 1
was STEP 1 the one that ran to 68 weeks or am i mixing them up
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STEP is several trials, so saying STEP said x is usually wrong without a number after it
compounded and brand felt the same to me at 0.25, which is one person and nothing more
2.4 is the ceiling
slower worked better
lost about 30kg on the low doses before i even got to 1, which surprised me, thats one data point
wk 1-4 0.25mg
wk 5-10 0.50mg (held 2 extra weeks)
wk 11-14 1.00mg
wk 15-26 1.70mg (held, long)
wk 27+ 2.40mgslightly off topic but is the plateau at 7 weeks normal or am i doing something wrong
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back after 2 months off, do i restart at 0.25 or somewhere higher
[edited]STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping
moving my dose day by a day or two never did anything noticeable for me
Testing queue: 5 submissions open, 104 awaiting dispatch.
give it four weeks
right so my Medutest report on the BCH vial came back 96.8 against a certificate saying 99.2
*Medutest not the other one
08:35marrow.mod pinned a message