vialroom

#semaglutide 2025-12-30

Tuesday19 messages5 participantstimes are UTC
Highlights from this day
  • half_life_hal — FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure 18:11
  • half_life_hal — back after 25 months off, do i restart at 0.25 or somewhere higher 18:12
  • per_mg_pete — quick one i dont think the plateau is a dose problem most of the time, but i cant prove that, not advice obviously moving my dose day by a day or two never did… 18:16
  • per_mg_pete — how many weeks before you noticed anything at 15 19:08

seven days ish

if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule, thats just me

anyone gone from 0.5 straight to 1 or is that too big a jump

HL

i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication

my 10 vial in 5ml gives 8mg/ml so 10 lands on 25 units, thats why i picked that volume

FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure

📈2👍8

back after 25 months off, do i restart at 0.25 or somewhere higher

Cited study
Semaglutide vs Liraglutide for Weight Loss in Adults with Overweight or Obesity (STEP 8)
JAMA · 2022
Weekly against daily, head to head.

SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial, your mileage will differ

PM

quick one i dont think the plateau is a dose problem most of the time, but i cant prove that, not advice obviously
moving my dose day by a day or two never did anything noticeable for me

💀16
DD

€240 a month for compounded against what brand costs locally is why most people here use vials

PM

how many weeks before you noticed anything at 15

Cited study
Tirzepatide versus Semaglutide Once Weekly in Type 2 Diabetes (SURPASS-2)
New England Journal of Medicine · 2021
The head-to-head everyone quotes. Note the semaglutide comparator dose.
PM

did anybody find a difference between QSC and pharmacy at the same 10

held at 2.4 and lost 104lb over 5 months, slower than the trials and fine by me