vialroom

#semaglutide 2026-01-02

Friday21 messages5 participantstimes are UTC
Highlights from this day
  • ghk_gia — i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication vial units and pen clicks are different systems, mixing the two is… 22:55
  • ghk_gia — moving my dose day by a day or two never did anything noticeable for me 22:59
  • cricket_or_footy — the appetite effect faded for me around 14 months and going up fixed it for a while, anyway 23:04
  • cricket_or_footy — my VendorInvestigate report on the Homopeptide vial came back 99 against a certificate saying 99.2 23:09
  • new_here_nat — is there a reason to hold at 1.7 rather than going to 2.4 23:55
LN

genuine question changed my mind on the four week rule, i think it depends entirely on how the current dose feels, we shall see

GG

the plateau hit me at 32 weeks and moved again about a month later without a dose change

i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
vial units and pen clicks are different systems, mixing the two is how people end up wrong

went too fast once

1

moving my dose day by a day or two never did anything noticeable for me

👍13🔥3💀16

half life is about a week so youre roughly four to five weeks to steady state on any new dose

5 months at 2.4 and the honest summary is diminishing returns after the first half

CO

the appetite effect faded for me around 14 months and going up fixed it for a while, anyway

wk 1-4    0.25mg
wk 5-10   0.50mg   (held 2 extra weeks)
wk 11-14  1.00mg
wk 15-26  1.70mg   (held, long)
wk 27+    2.40mg

my VendorInvestigate report on the Homopeptide vial came back 99 against a certificate saying 99.2

i dont think the plateau is a dose problem most of the time, but i cant prove that, anyway

GG

licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose

NH

brand vs compounded, is there a difference people can actually feel

NH

does the licensed ceiling for weight differ from the diabetes one
compounded and brand felt the same to me at 15, which is one person and nothing more

NH

dose day is sunday for me only because thats when i remember, not because sunday matters

NH

is there a reason to hold at 1.7 rather than going to 2.4

[edited]
Cited study
Once-Weekly Semaglutide in Adults with Overweight or Obesity and Type 2 Diabetes (STEP 2)
The Lancet · 2021
The type 2 diabetes population, where the weight response is generally smaller.