slower worked better
🧊6❤️2📈5
#semaglutide 2026-01-11
Sunday24 messages7 participantstimes are UTC
Highlights from this day
did anyone hold at 2.5 longer than four weeks before going up
lost about 34kg on the low doses before i even got to 1, which surprised me
for the archive anyone gone from 10 straight to 2 or is that too big a jump
does moving my dose day by two days matter with a seven day half life
SELECT wasnt weight
24 months at 2.4 and the honest summary is diminishing returns after the first half
🔥2📈13
was SURMOUNT-1 the one that ran to 68 weeks or am i mixing them up
went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step
licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose
👍14
dose day is sunday for me only because thats when i remember, not because sunday matters
i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
how long till steady state, ive read the half life is about a week
SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
steady state takes weeks
i dont think the plateau is a dose problem most of the time, but i cant prove that, ask me again in a month
five week steps worked better for me than four, purely on how the second week felt, from memory
not the same trial
[edited]| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
the plateau hit me at 31 weeks and moved again about a month later without a dose change
Channel stats, last 30 days: 25 messages from 33 members.
compounded and brand felt the same to me at 2, which is one person and nothing more
changed my mind on the four week rule, i think it depends entirely on how the current dose feels
anyone compared their 10 vial dosing against the pen increments
vials not pens here
vial units and pen clicks are different systems, mixing the two is how people end up wrong
[edited]