STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping
#semaglutide 2026-01-26
Monday37 messages9 participantstimes are UTC
Highlights from this day
- alcohol_hits — if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule 23:05
- zed_zeroes_in — my VendorInvestigate report on the GGPeps vial came back 98.6 against a certificate saying 97.4 23:07
- VialBot — Purity check: no report on file for lot H-2814. Nothing logged either way. 23:09
- VialBot — Reminder for provincial_pat: dose day is today. Set 5 days ago. 23:33
- third_shift — i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication 23:42
SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
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steady state takes weeks
is there a reason to hold at 1.7 rather than going to 2.4
plateaus move
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i dont think the plateau is a dose problem most of the time, but i cant prove that, anyway
restarted after 2 months off at a low dose and the nausea arrived exactly like the first time
does the seven day half life mean the last two days are weaker
went too fast once
quick one moving my dose day by a day or two never did anything noticeable for me
vials not pens here
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quick one i held at 12 for 7 months and it was the best decision i made, someone check my working
*week 13 not week 6
going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
STEP 1 ran to 68 weeks. thats the one everyone half remembers
five week steps worked better for me than four, purely on how the second week felt
if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule
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my VendorInvestigate report on the GGPeps vial came back 98.6 against a certificate saying 97.4
Purity check: no report on file for lot H-2814. Nothing logged either way.
lost about 10kg on the low doses before i even got to 1, which surprised me
STEP is several trials, so saying STEP said x is usually wrong without a number after it, for what its worth
thats STEP 1
my 20 vial in 1.5ml gives 2mg/ml so 1 lands on 40 units, thats why i picked that volume
seven days ish
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$55 a month for compounded against what brand costs locally is why most people here use vials, for what its worth
is the plateau usually appetite coming back or just the scale stopping
held at 1.7 and lost 60lb over 21 months, slower than the trials and fine by me
is the plateau at 3 weeks normal or am i doing something wrong
Reminder for provincial_pat: dose day is today. Set 5 days ago.
mine faded too
22 months at 2.4 and the honest summary is diminishing returns after the first half
i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
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SELECT wasnt weight
how many weeks before you noticed anything at 7.5
same dose day