my 40 vial in 1.5ml gives 8mg/ml so 10 lands on 15 units, thats why i picked that volume
#semaglutide 2026-03-12
Thursday32 messages9 participantstimes are UTC
Highlights from this day
- night_pin — right so went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down 17:02
- mg_per_ml — went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step 17:37
- VialBot — Verification log updated: ERP — evidence added, status unchanged. 17:52
- no_appetite_nia — how long till steady state, ive read the half life is about a week 18:12
right so went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down
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STEP 1 ran to 68 weeks. thats the one everyone half remembers
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did the STEP 4 withdrawal arm show what i think it showed
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SELECT wasnt weight
[edited]going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
steady state takes weeks
went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step
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lost about 20kg on the low doses before i even got to 1, which surprised me
moving my dose day by a day or two never did anything noticeable for me
Verification log updated: ERP — evidence added, status unchanged.
seven days ish
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does moving my dose day by two days matter with a seven day half life
how long till steady state, ive read the half life is about a week
wk 1-4 0.25mg
wk 5-10 0.50mg (held 2 extra weeks)
wk 11-14 1.00mg
wk 15-26 1.70mg (held, long)
wk 27+ 2.40mg$94 a month for compounded against what brand costs locally is why most people here use vials
8 months at 2.4 and the honest summary is diminishing returns after the first half
went too fast once
give it four weeks
the plateau hit me at 9 weeks and moved again about a month later without a dose change
i dont think the plateau is a dose problem most of the time, but i cant prove that
same dose day
plateaus move
moving my dose day by a day or two never did anything noticeable for me
FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure
steady state is the bit people skip, judging a new dose after eight days tells you almost nothing
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i stayed on 1.7 for 17 months and never went to 2.4, appetite was already where i needed it
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compounded and brand felt the same to me at 12, which is one person and nothing more
is 2.4 the top or do people go past it
back after 20 months off, do i restart at 0.25 or somewhere higher
vials not pens here
peptidemeter-summary-c-4402.pdf
2 pages · 304 KB · not retained in the public archive
if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule
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my dose day drifted from friday to sunday, does that reset anything
the appetite effect faded for me around 2 months and going up fixed it for a while
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anyone gone from 15 straight to 2.5 or is that too big a jump