how long till steady state, ive read the half life is about a week
dose day is sunday for me only because thats when i remember, not because sunday matters
#semaglutide 2026-04-07
Tuesday17 messages5 participantstimes are UTC
Highlights from this day
- gip_glp_gil — how long till steady state, ive read the half life is about a week dose day is sunday for me only because thats when i remember, not because sunday matters 18:37
- gip_glp_gil — my plateau was the scale stopping while appetite stayed suppressed, which is a different problem, i think 18:40
- nausea_window — SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial 18:48
- gip_glp_gil — my 30 vial in 1ml gives 5mg/ml so 5 lands on 15 units, thats why i picked that volume, ill dig out the number 19:20
- escalation_anxiety — for the archive the long half life flattens the trough more than people expect, i never felt a day seven dip 20:42
my plateau was the scale stopping while appetite stayed suppressed, which is a different problem, i think
same dose day
coming back to this im at 1 and stuck, did anyone break a plateau without going up
did the STEP 4 withdrawal arm show what i think it showed
SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
held there too
while im here does anyone actually run a five week step instead of four
my 30 vial in 1ml gives 5mg/ml so 5 lands on 15 units, thats why i picked that volume, ill dig out the number
steady state takes weeks
is there a reason to hold at 1.7 rather than going to 2.4
not the same trial
✅13
changed my mind on the four week rule, i think it depends entirely on how the current dose feels
for the archive the long half life flattens the trough more than people expect, i never felt a day seven dip
⚠️8💀1✅10
FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure
genuine question held at 2.4 and lost 14lb over 18 months, slower than the trials and fine by me
2.4 is the ceiling