#semaglutide 2026-06-01

changed my mind on the four week rule, i think it depends entirely on how the current dose feels

seven days ish

if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule, someone check my working

while im here did anyone hold at 2.4 longer than four weeks before going up

not the same trial

im 21 months in at 5 and the appetite effect faded, is that a thing

Reminder for rotterdam_recon: dose day is today. Set 9 days ago.

vial units and pen clicks are different systems, mixing the two is how people end up wrong

SELECT wasnt weight

FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure, from memory

Verification log updated: MKM — evidence added, status unchanged.

does anyone actually run a five week step instead of four

my plateau was the scale stopping while appetite stayed suppressed, which is a different problem
the appetite effect faded for me around 24 months and going up fixed it for a while

2.4 is the ceiling

steady state takes weeks

did anybody find a difference between WXT and pharmacy at the same 1

vials not pens here

going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution

genuine question what did SELECT actually measure, i see it quoted for everything

went too fast once

quick one how long till steady state, ive read the half life is about a week

same dose day