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Thread · #semaglutide · 2025-02-06

steady state is the bit people skip, judging a

Spun off from a message in #semaglutide on 2025-02-06. 13 messages, 3 participants.

The message this came from
  • hot_mailbox — steady state is the bit people skip, judging a new dose after eight days tells you almost nothing 22:42
HM

half life is about a week so youre roughly four to five weeks to steady state on any new dose

A1

restarted after 25 months off at a low dose and the nausea arrived exactly like the first time

MC

i dont think the plateau is a dose problem most of the time, but i cant prove that

[edited]
A1

FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure

A1

did the STEP 4 withdrawal arm show what i think it showed

MC

went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down

MC

the appetite effect faded for me around 2 months and going up fixed it for a while