i tracked weekly for two years and the trend only ever made sense at a four week rolling average, and nobody here is a clinician
Thread · #semaglutide · 2025-08-09
half life is about a week so youre roughly
Spun off from a message in #semaglutide on 2025-08-09. 11 messages, 4 participants.
The message this came from
- drawup_dee — half life is about a week so youre roughly four to five weeks to steady state on any new dose, i held at 1.7 for months 10:58
if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule
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will try that, score out of five
on the ladder licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose
does the seven day half life mean the last two days are weaker
changed my mind on the four week rule, i think it depends entirely on how the current dose feels, the population is not us
the day either side of the interval has never mattered for me and the half life makes that unsurprising
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held at 15 a long time so five week steps worked better for me than four, purely on how the second week felt, plotted over a year
plotting a year of this i stayed on 1.7 for 25 months and never went to 2.4, appetite was already where i needed it, four week average, not weekly
a missed week was not a restart for me, i carried on and the week after felt like a slightly stronger dose
one step only