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Thread · #semaglutide · 2025-09-26

how do people decide theyve found their dose rather

Spun off from a message in #semaglutide on 2025-09-26. 16 messages, 5 participants.

The message this came from
  • snac_and_water — one for the chart people how do people decide theyve found their dose rather than their tolerance, first time doing this 19:50
NH

i asked for the vial rather than the pen for cost reasons and the arithmetic became my problem, which is a fair trade, that is the licensed ladder anyway

❤️17

the top dose is not a target. plenty of people here sit at 1mg indefinitely and are perfectly happy, not medical advice

MU

one for the chart people did anyone hold at 1 longer than four weeks before going up, happy to be told to read the pin

MM

the long half life flattens the trough more than people expect, i never felt a day seven dip

VL

the difference between my best week and my worst week at one dose is bigger than any step change i ever made, four week average, not weekly

📈12

came back down

MU

i log the dose, the date and one sentence, and the pattern only shows up over quarters

👀9
NH

the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing

SA

restarted after 26 months off at a low dose and the nausea arrived exactly like the first time

NH

did anyone hold at 2.5 for longer than the schedule suggested and regret it

⚠️3👍11