day two is the worst
dose day = d0
0.25mg nothing much
0.50mg d1-d2 mild
1.00mg d1-d3 moderate
1.70mg d1-d2 moderate, d4 fine
2.40mg d1 rough, gone by d3#side-effects 2026-03-10
Tuesday65 messages12 participantstimes are UTC
Highlights from this day
- VialBot — Channel stats, last 30 days: 16 messages from 47 members. 16:08
- hydrate_hana — while im here powering through is how people quit entirely. reducing is how people stay on it 17:08
- dez_domains — i lost my gallbladder in 2024 and i tell people that not to frighten them but because slowing down is free 18:50
- rowan_reads — severe persistent pain radiating to the back, or repeated vomiting you cannot keep water down through, is not a chat question, ill dig out the number escalation is… 19:53
- rowan_reads — i had gallstones confirmed on a scan after losing quickly. slow down if you can 19:54
does eating before or after the injection make any difference
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water first, then fibre, then magnesium, then a softener, then a pharmacist. in that order
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dont push through
the dose day matters more than the dose for the GI stuff, at least for me
that settles
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sorry to jump in my injection site itched for three days, normal
[edited]slightly off topic but is the nausea meant to be worst around day 9 or is that just me
whats actually worked for anyone on the constipation, ive tried everything
please get seen
how do you cope with the smell of food when nothing is appealing
the shed usually starts month three to four and usually stops. it tracks how fast you are losing
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Purity check: no report on file for lot KP-0925. Nothing logged either way.
coming back after 11 months off: do the side effects reset
a lot of what people call fatigue on this stuff turns out to be dehydration or undereating
electrolytes made more difference to my fatigue than anything else i tried
ginger did nothing for me and worked for two other people here. thats where the evidence is at
[edited]sulphur burps. is there anything at all that helps
*PeptideMeter not the other one
nobody here can tell you whether a symptom is serious. we can tell you the ones that are always worth checking
Channel stats, last 30 days: 16 messages from 47 members.
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protein and iron are worth checking if the hair thing is dragging on past six months, i could be wrong
drop a rung
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dropping back a rung for a fortnight is a completely legitimate move
if a side effect is new and severe rather than familiar and annoying, that is the line
new severe right upper quadrant pain after fast weight loss is a get seen situation
it got better for me
follow up how long did it take for the GI stuff to actually settle for you
if you have stopped enjoying food entirely and are not eating, say so, we will help you build meals, anyway
update from 3 months ago: the nausea did settle, around week seven, completely
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magnesium
update on the earlier thing is it the dose or the escalation that causes the nausea
reflux getting worse is documented enough that it is worth mentioning to a prescriber
hope it settles
protein
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while im here powering through is how people quit entirely. reducing is how people stay on it
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the burps started at 5 and not before, has anyone else had that
New independent result logged — MKM, lot D-0718, purity 97.4% (PeptideMeter).
im at week 29 and eating maybe 900 calories without trying to, is that a problem
the sulphur burps seem to track fatty meals for a lot of people here, including me
eat more
right upper side pain on and off for a week, should i be worried
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sorry youre having a rough one
escalation is when most of the trouble happens, not the absolute dose
[edited]my resting heart rate went up a few bpm and stayed there. worth logging from baseline
my resting heart rate is up about 6 bpm, is that a known thing
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anyone get properly wiped out for a day or two after the dose
taste changes settled for me around week eight and never fully came back, for what its worth
i lost my gallbladder in 2024 and i tell people that not to frighten them but because slowing down is free
| Step | What | Give it |
|---|---|---|
| 1 | water, properly, all day | 3 days |
| 2 | soluble fibre | 4 days |
| 3 | magnesium | 3 days |
| 4 | stool softener | 3 days |
| 5 | pharmacist | now |
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nausea is usually worst somewhere in the first 24 to 72 hours after the dose and then eases
rotate the site
dose day = d0
0.25mg nothing much
0.50mg d1-d2 mild
1.00mg d1-d3 moderate
1.70mg d1-d2 moderate, d4 fine
2.40mg d1 rough, gone by d3fibre before pills
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right so i keep a one line note per day. it is the only way i could see the pattern
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do you drop back a dose for side effects or push through
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update on the earlier thing week 6 and still nauseous, at what point is this not going to settle
thats not a chat question
unrelated but everything tastes metallic since i went up, does that settle
Batch lookup SG-1177: 7 independent reports on file, earliest 2025-11-07.
has anyone had reflux specifically get worse rather than better
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slightly off topic but anyone had the fatigue turn out to be something boring like not drinking enough
new severe right upper quadrant pain after fast weight loss is a get seen situation
severe persistent pain radiating to the back, or repeated vomiting you cannot keep water down through, is not a chat question, ill dig out the number
escalation is when most of the trouble happens, not the absolute dose
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i had gallstones confirmed on a scan after losing quickly. slow down if you can
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anyone found the fatigue lifted when they fixed their protein
site itching is common and rotation fixed it for most people i have seen post about it, your mileage will differ
same at week 3
the hiccups are real, nobody knows why, they seem to fade after a few doses