drop a rung
#side-effects 2026-05-06
Wednesday52 messages10 participantstimes are UTC
Highlights from this day
- bench_notes — severe persistent pain radiating to the back, or repeated vomiting you cannot keep water down through, is not a chat question, for what its worth 16:35
- coffee_only — week 4 and still nauseous, at what point is this not going to settle 17:20
- chlorhex — i lost my gallbladder in 2024 and i tell people that not to frighten them but because slowing down is free 19:14
- fibre_first — is it the dose or the escalation that causes the nausea 19:58
reflux getting worse is documented enough that it is worth mentioning to a prescriber
[edited]im at week 18 and eating maybe 900 calories without trying to, is that a problem
severe persistent pain radiating to the back, or repeated vomiting you cannot keep water down through, is not a chat question, for what its worth
[edited]fridge-thermometer.png
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nausea is usually worst somewhere in the first 24 to 72 hours after the dose and then eases
unrelated but update from 25 months ago: the nausea did settle, around week seven, completely
the hiccups are real, nobody knows why, they seem to fade after a few doses
if you have stopped enjoying food entirely and are not eating, say so, we will help you build meals
the shed usually starts month three to four and usually stops. it tracks how fast you are losing, ask me again in a month
has anyone had reflux specifically get worse rather than better
water first
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electrolytes made more difference to my fatigue than anything else i tried, happy to be corrected
powering through is how people quit entirely. reducing is how people stay on it
eating small and often was the only thing that made the first month liveable for me
magnesium
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anyone get properly wiped out for a day or two after the dose
genuine question my resting heart rate went up a few bpm and stayed there. worth logging from baseline
week 4 and still nauseous, at what point is this not going to settle
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coming back after 16 months off: do the side effects reset
if you are under 1000 calories by accident that is a problem, not discipline
new severe right upper quadrant pain after fast weight loss is a get seen situation
ginger did nothing for me and worked for two other people here. thats where the evidence is at
protein
if you are under 1000 calories by accident that is a problem, not discipline, thats just me
what did your gallbladder symptoms actually feel like before it got diagnosed
electrolytes made more difference to my fatigue than anything else i tried
ok so a lot of what people call fatigue on this stuff turns out to be dehydration or undereating
the sulphur burps seem to track fatty meals for a lot of people here, including me
site itching is common and rotation fixed it for most people i have seen post about it
while im here the dose day matters more than the dose for the GI stuff, at least for me
sorry to jump in how do you cope with the smell of food when nothing is appealing
it got better for me
apob_over_ldlwhile im here the dose day matters more than the dose for the GI stuff, at least for me
i keep a one line note per day. it is the only way i could see the pattern
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water first, then fibre, then magnesium, then a softener, then a pharmacist. in that order
day two is the worst
sulphur burps. is there anything at all that helps
my injection site itched for three days, normal
fibre before pills
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i lost my gallbladder in 2024 and i tell people that not to frighten them but because slowing down is free
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sorry youre having a rough one
dropping back a rung for a fortnight is a completely legitimate move
new severe right upper quadrant pain after fast weight loss is a get seen situation
protein and iron are worth checking if the hair thing is dragging on past six months
do you drop back a dose for side effects or push through
hiccups. every single time. why
if a side effect is new and severe rather than familiar and annoying, that is the line
is it the dose or the escalation that causes the nausea
| Step | What | Give it |
|---|---|---|
| 1 | water, properly, all day | 3 days |
| 2 | soluble fibre | 4 days |
| 3 | magnesium | 3 days |
| 4 | stool softener | 3 days |
| 5 | pharmacist | now |
that settles
i had gallstones confirmed on a scan after losing quickly. slow down if you can
escalation is when most of the trouble happens, not the absolute dose
nobody here can tell you whether a symptom is serious. we can tell you the ones that are always worth checking
*VendorInvestigate not the other one
slightly off topic but taste changes settled for me around week eight and never fully came back
rotate the site
hope it settles