vialroom

#storage-coldchain 2024-12-08

Sunday16 messages4 participantstimes are UTC
Highlights from this day
  • brisbane_bac — do i need to worry about light exposure or is that overthinking i freeze aliquots and have had them test fine afterwards. others here would not do it and i understand… 10:01
  • underfill_uma — lyophilised powder is genuinely robust. a warm transit is far less likely to matter than people fear 10:29
  • underfill_uma — coming back to this do you keep the unopened vials and the in-use one in the same place 12:55
  • underfill_uma — i left it out overnight by accident, bin it or use it 12:56
BB

do i need to worry about light exposure or is that overthinking
i freeze aliquots and have had them test fine afterwards. others here would not do it and i understand why

buy a thermometer. mine reads 5.6 on the door and two degrees lower at the back

parcel sat in a hot mailbox for 5 hours, is it dead

UU

two to eight degrees. most domestic fridge doors are not in that range and people do not check

UU

lyophilised powder is genuinely robust. a warm transit is far less likely to matter than people fear

my fridge is 3.1

UU

coming back to this do you keep the unopened vials and the in-use one in the same place

🤝17

i left it out overnight by accident, bin it or use it

ConditionLyophilisedReconstituted
2-8 °Cfine, long termfine, weeks
Room temp, daysfine in every report herereported fine, shorter
Room temp, weeksreported finedo not
Warm transit, 30 °C+no failure loggedone visible degradant peak
Frozen oncefinecontested, no consensus
Freeze-thaw cycledfinethe room says no

a few hours at room temperature is almost certainly nothing. a week is a different conversation