vialroom

#storage-coldchain 2025-04-21

Monday21 messages6 participantstimes are UTC
Highlights from this day
  • travel_cooler — update from 5 months ago: replaced the fridge, temperature is stable, no more anxiety 13:58
  • deadspace — i freeze aliquots and have had them test fine afterwards. others here would not do it and i understand why a liquid cold pack tells you it was above freezing, not… 14:27
  • plus_sixteen — how long is reconstituted actually good for at room temperature a liquid cold pack tells you it was above freezing, not that your vial cooked 15:28

the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in

cold pack arrived completely liquid, does that mean anything

TC

update from 5 months ago: replaced the fridge, temperature is stable, no more anxiety

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DE

i freeze aliquots and have had them test fine afterwards. others here would not do it and i understand why
a liquid cold pack tells you it was above freezing, not that your vial cooked

DE

i have never had a lyophilised vial fail after a warm transit and i have had some bad ones

lyophilised powder is genuinely robust. a warm transit is far less likely to matter than people fear

PS

how long is reconstituted actually good for at room temperature
a liquid cold pack tells you it was above freezing, not that your vial cooked

for flying, hand luggage every time. the hold is not temperature controlled the way people assume, i have it written down somewhere

freeze thaw cycling is the risk, not one freeze. that is my read of it anyway

what temperature does a domestic fridge door actually swing to

for the archive reconstituted solution is the fragile part. that is where the cold chain actually earns its keep

TT

coming back to this do i need to worry about light exposure or is that overthinking

TT

buy a thermometer. mine reads 6.2 on the door and two degrees lower at the back, thats just me